Common side effects of Vagifem include:. The initial dose of Vagifem is one tablet, femhrt and blood pressure, inserted vaginally, once daily for two weeks, at the same time each day, femhrt and blood pressure. The maintenance dose is one tablet, inserted vaginally, twice weekly. Some products that may interact with Vagfem low cholesterol meat and fish aromatase inhibitors, femhrt and blood pressure, raloxifenetamoxifenor toremifene.
Tell your doctor all medications you are taking. Vagifem must not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor immediately. This medication passes into breast milk. It may reduce the quality and amount of breast milk produced. Consult your doctor before breastfeeding. Our Vagifem estradiol vaginal Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Femhrt and blood pressure your doctor for medical advice about side effects. Get emergency medical help if you have any of these signs of an allergic reaction: Remove the vaginal ring and seek emergency medical attention if you have: These may be signs of a life-threatening disease called toxic shock syndrome. Read the entire detailed patient monograph for Vagifem Estradiol Vaginal Tablets. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
In a month randomized, double-blind, parallel group, placebo-controlled study, a total of postmenopausal women were randomized to receive either placebo or Vagifem 10 mcg inserts, femhrt and blood pressure.
In a week, randomized, double-blind, placebo-controlled study, postmenopausal women were randomized to receive either placebo or Vagifem 25 femhrt and blood pressure inserts, femhrt and blood pressure. The following adverse reactions have been identified during post-approval use of Vagifem 25 mcg. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Endometrial cancerendometrial hyperplasiavaginal irritation, vaginal pain, vaginismusvaginal ulceration. Urticariaerythematous or pruritic rash, genital pruritus. Aggravated migrainedepression, insomnia. Fluid retention, weight increase, drug ineffectiveness, hypersensitivity, blood estrogen increase. Additional postmarketing adverse reactions have been reported in patients receiving other forms of hormone therapy.
Last reviewed on RxList: Vagifem Side Effects Center. Find Lowest Prices on. Take the Menopause Quiz. Menopause and Perimenopause Slideshow. Call your doctor at once if you have: Common side effects may include: Postmarketing Experience The following adverse reactions have been identified during post-approval use of Vagifem 25 mcg.
Genitourinary System Endometrial cancerendometrial hyperplasiavaginal irritation, vaginal pain, vaginismusfemhrt and blood pressure, vaginal ulceration Breast Breast cancer Cardiovascular Deep vein thrombosis Gastrointestinal Diarrhea Skin Urticariaerythematous or pruritic rash, genital pruritus Central Nervous System Aggravated migrainedepression, insomnia Miscellaneous Fluid retention, weight increase, drug ineffectiveness, hypersensitivity, blood estrogen increase Additional postmarketing adverse reactions have been reported in patients receiving other forms of hormone therapy.
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