D-Limonene: safety and clinical applications.

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The D limonene Experience. Beware!

Limonene and cancer

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Some medications are limonene and cancer and broken down by the liver. Taking limonene along with some medications that are changed by the liver can lead to a variety of effects and side effects.

Before taking limonene talk to your healthcare provider if you take any medications that are changed by the liver. Limonene might be broken down by the liver. Taking limonene along with medications that decrease the break down of limonene in the liver might increase the effects and side effects of limonene. Taking limonene along with medications that increase the break down of limonene in the liver might folic acid receptors and lung cancer the effects of limonene, limonene and cancer.

At this time there is not enough scientific information to determine an appropriate range of doses for limonene. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using. It is used to make medicine. Limonene is used to promote weight losslimonene and cancer, prevent cancertreat cancerand treat bronchitis.

In foods, beverages, and chewing gum, limonene is used as a flavoring. In pharmaceuticals, limonene is added to help medicinal ointments and creams penetrate the skin. In manufacturing, limonene is used as a fragrance, limonene and cancer, cleaner solventand as an ingredient in water-free hand cleansers, limonene and cancer.

How does it work? Limonene may block cancer-forming chemicals and kill cancer cells in the laboratory, limonene and cancer. But more research is needed to know if this occurs in humans. Insufficient Evidence for Cancer treatment. One form of limonene D-limonene seems to build up in tumors in people with advanced cancerwhen it is taken by mouth in day cycles. More evidence is needed to rate the effectiveness of limonene for these uses. It also appears to be safe for most people in medicinal amounts when taken by mouth for up to one year.

Pregnancy and breast -feeding: Stay on the safe side and avoid using limonene as a medicine until more is known. Moderate Interaction Be cautious with this combination. Prevention and therapy of cancer by dietary monoterpenes. Biotransformation of limonene by bacteria, fungi, yeasts, and plants. Appl Microbiol Biotechnol ; Electronic Code of Federal Regulations. Hum Exp Toxicol ; Oxidized citrus oil R-limonene: J Am Acad Dermatol ; Drug Metab Dispos ; Evaluation of limonene and cancer absorption of midazolam by terpenes.

Drug Metab Pharmacokinet ; Raphael TJ, Limonene and cancer G. Immunomodulatory activity of naturally occurring monoterpenes carvone, limonene, and perillic acid. D-Limonene contact dermatitis from hand cleansers.

The male rat carcinogens limonene and sodium saccharin are not mutagenic to male Big Blue rats. Phase I and pharmacokinetic study of D-limonene in patients with advanced cancer. Cancer Chemother Pharmacol ; Show More Show Less.


Limonene and cancer